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Accueil > R&D > Publications

2016

par Sebastien Janel - publié le , mis à jour le

Flow cytometry

Synthesis and Biological Evaluation of N‑[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide(ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agentswith Potent in Vivo Antitumor Activity. Zacharie Segaoula, Julien Leclercq,Valérie Verones,Nathalie Flouquet, Marie Lecoeur, Lionel Ach, Nicolas Renault, Amélie Barczyk, Patricia Melnyk, Pascal Berthelot, Xavier Thuru, and Nicolas Lebegue. Journal of Medicinal Chemistry August 18, 2016

Atomic Force Microscopy

High potential of adhesion to biotic and abiotic surfaces by opportunistic Staphylococcus aureus strains isolated from orthodontic appliances. A. Merghni, M. Ben Nejma, I. Dallel, S. Tobji, A. Ben Amor, S. Janel, F. Lafont, M. Aouni, and M. Mastouri. Microb. Pathog., vol. 91, pp. 61–67, 2016.

Photonic Microscopy

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer’s Disease. Letronne F, Laumet G, Ayral AM, Chapuis J, Demiautte F, Laga M, Vandenberghe ME, Malmanche N, Leroux F, Eysert F, Sottejeau Y, Chami L, Flaig A, Bauer C, Dourlen P, Lesaffre M, Delay C, Huot L, Dumont J, Werkmeister E, Lafont F, Mendes T, Hansmannel F, Dermaut B, Deprez B, Hérard AS, Dhenain M, Souedet N, Pasquier F, Tulasne D, Berr C, Hauw JJ, Lemoine Y, Amouyel P, Mann D, Déprez R, Checler F, Hot D, Delzescaux T, Gevaert K, Lambert JC. EBioMedicine. 2016 Jul ;9:278-92. doi : 10.1016/j.ebiom.2016.06.002.

Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection. Sangaré LO, Alayi TD, Westermann B, Hovasse A, Sindikubwabo F, Callebaut I, Werkmeister E, Lafont F, Slomianny C, Hakimi MA, Van Dorsselaer A, Schaeffer-Reiss C, Tomavo S.
Nat Commun. 2016 Apr 11 ;7:11191. doi : 10.1038/ncomms11191.

HCS

Barthe P, Veyron-Churlet R, de Visch A, Gilleron M, Saliou JM, Tomavo S, Nigou J, Brodin P, Cohen-Gonsaud M Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization Structure 24 1788-1794 2016

Chapuis J, Flaig A, Grenier-Boley B, Eysert F, Pottiez V, Deloison G, Vandeputte A, Ayral AM, Mendes T, Desai S, Goate AM, Kauwe JS, Leroux F, Herledan A, Demiautte F, Bauer C, Checler F, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Albert M, Moghekar A, O’Brien R, Peskind ER, Malmanche N, Schellenberg GD, Dourlen P, Song OR, Cruchaga C, Amouyel P, Deprez B, Brodin P, Lambert JC Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism Acta Neuropathol 2016 2016

Galani BR, Sahuc ME, Sass G, Njayou FN, Loscher C, Mkounga P, Deloison G, Brodin P, Rouille Y, Tiegs G, Seron K, Moundipa PF Khaya grandifoliola C.DC : a potential source of active ingredients against hepatitis C virus in vitro Arch Virol 161 1169-1181 2016

Nikiforov PO, Surade S, Blaszczyk M, Delorme V, Brodin P, Baulard AR, Blundell TL, Abell C A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters Org Biomol Chem 14 2318-2326 2016

Queval CJ, Song OR, Deboosere N, Delorme V, Debrie AS, Iantomasi R, Veyron-Churlet R, Jouny S, Redhage K, Deloison G, Baulard A, Chamaillard M, Locht C, Brodin P STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection Sci Rep 629297 2016

Song OR, Marion E, Comoglio Y, Babonneau J, Guerineau N, Sandoz G, Yeramian E, Brodin P, Marsollier L. Mycolactone : the amazing analgesic mycobacterial toxin Med Sci (Paris) 32 156-158 2016